| CRNX |
Crinetics Pharmaceuticals, Inc. |
4.97B |
3.81% |
|
|
|
|
|
53.60 |
1.63% |
49.15% |
47.46% |
|---|
| ALKS |
Alkermes plc |
4.81B |
3.69% |
|
|
|
|
|
29.71 |
-0.87% |
46.26% |
66.15% |
|---|
| AXSM |
Axsome Therapeutics, Inc. |
4.40B |
3.37% |
|
|
|
|
|
90.73 |
1.10% |
117.03% |
96.34% |
|---|
| RNA |
Avidity Biosciences, Inc. |
3.80B |
2.91% |
|
|
|
|
|
31.82 |
2.48% |
62.95% |
21.24% |
|---|
| PTCT |
PTC Therapeutics, Inc. |
3.57B |
2.74% |
|
|
|
|
|
46.24 |
2.19% |
78.18% |
26.50% |
|---|
| RYTM |
Rhythm Pharmaceuticals, Inc. |
3.45B |
2.65% |
|
|
|
|
|
56.12 |
1.15% |
50.53% |
14.31% |
|---|
| VRNA |
Verona Pharma plc |
3.44B |
2.64% |
|
|
|
|
|
42.02 |
1.94% |
67.19% |
14.29% |
|---|
| MLTX |
MoonLake Immunotherapeutics |
3.29B |
2.52% |
|
|
|
|
|
52.17 |
0.56% |
46.85% |
7.92% |
|---|
| DNLI |
Denali Therapeutics Inc. |
3.09B |
2.37% |
|
|
|
|
|
21.45 |
-0.19% |
64.50% |
52.72% |
|---|
| XENE |
Xenon Pharmaceuticals Inc. |
2.95B |
2.26% |
|
|
|
|
|
38.63 |
-0.69% |
42.31% |
48.27% |
|---|
| FOLD |
Amicus Therapeutics, Inc. |
2.93B |
2.25% |
|
|
|
|
|
9.80 |
0.72% |
51.14% |
50.18% |
|---|
| ZLAB |
Zai Lab Limited |
2.91B |
2.24% |
|
|
|
|
|
26.72 |
1.91% |
68.37% |
11.98% |
|---|
| EWTX |
Edgewise Therapeutics, Inc. |
2.91B |
2.24% |
|
|
|
|
|
30.78 |
-0.06% |
89.24% |
14.36% |
|---|
| MRUS |
Merus N.V. |
2.87B |
2.20% |
|
|
|
|
|
41.85 |
-0.57% |
65.96% |
15.68% |
|---|
| ACAD |
ACADIA Pharmaceuticals Inc. |
2.81B |
2.15% |
|
|
|
|
|
16.87 |
0.84% |
53.83% |
32.25% |
|---|
| VCEL |
Vericel Corporation |
2.79B |
2.14% |
|
|
|
|
|
56.50 |
2.82% |
52.61% |
36.15% |
|---|
| VERA |
Vera Therapeutics, Inc. |
2.70B |
2.07% |
|
|
|
|
|
42.60 |
1.31% |
53.85% |
14.67% |
|---|
| PTGX |
Protagonist Therapeutics, Inc. |
2.47B |
1.90% |
|
|
|
|
|
41.49 |
4.93% |
68.97% |
27.99% |
|---|
| NAMS |
NewAmsterdam Pharma Company N.V. |
2.72B |
1.81% |
|
|
|
|
|
25.50 |
0.16% |
60.33% |
5.54% |
|---|
| IDYA |
IDEAYA Biosciences, Inc. |
2.21B |
1.70% |
|
|
|
|
|
25.61 |
3.31% |
75.81% |
78.58% |
|---|
| APGE |
Apogee Therapeutics, Inc. |
2.79B |
1.65% |
|
|
|
|
|
47.71 |
1.47% |
54.06% |
48.74% |
|---|
| AKRO |
Akero Therapeutics, Inc. |
2.05B |
1.57% |
|
|
|
|
|
29.34 |
3.31% |
60.01% |
41.50% |
|---|
| TARS |
Tarsus Pharmaceuticals, Inc. |
2.02B |
1.55% |
|
|
|
|
|
52.91 |
1.75% |
95.92% |
66.61% |
|---|
| AGIO |
Agios Pharmaceuticals, Inc. |
2.02B |
1.55% |
|
|
|
|
|
35.42 |
-1.09% |
65.52% |
63.71% |
|---|
| MIRM |
Mirum Pharmaceuticals, Inc. |
1.99B |
1.53% |
|
|
|
|
|
41.51 |
0.92% |
65.33% |
43.01% |
|---|
| CGON |
CG Oncology, Inc. Common stock |
2.18B |
1.49% |
|
|
|
|
|
28.67 |
2.32% |
94.48% |
82.26% |
|---|
| IRON |
Disc Medicine, Inc. |
1.92B |
1.47% |
|
|
|
|
|
64.50 |
2.46% |
67.95% |
19.35% |
|---|
| MNKD |
MannKind Corporation |
1.89B |
1.45% |
|
|
|
|
|
6.85 |
8.73% |
64.11% |
41.80% |
|---|
| GLPG |
Galapagos NV |
1.76B |
1.36% |
|
|
|
|
|
26.76 |
1.48% |
78.52% |
47.88% |
|---|
| NMRA |
Neumora Therapeutics, Inc. Common Stock |
1.75B |
1.34% |
|
|
|
|
|
10.85 |
3.33% |
404.13% |
97.37% |
|---|
| XNCR |
Xencor, Inc. |
1.69B |
1.30% |
|
|
|
|
|
24.13 |
0.50% |
97.87% |
20.59% |
|---|
| CLDX |
Celldex Therapeutics, Inc. |
1.67B |
1.28% |
|
|
|
|
|
25.14 |
-0.95% |
88.20% |
62.75% |
|---|
| GPCR |
Structure Therapeutics Inc. |
1.60B |
1.23% |
|
|
|
|
|
27.90 |
-6.91% |
89.69% |
23.83% |
|---|
| BCRX |
BioCryst Pharmaceuticals, Inc. |
1.57B |
1.20% |
|
|
|
|
|
7.57 |
2.44% |
60.58% |
33.98% |
|---|
| VRDN |
Viridian Therapeutics, Inc. |
1.51B |
1.16% |
|
|
|
|
|
19.03 |
1.60% |
64.84% |
13.80% |
|---|
| PRAX |
Praxis Precision Medicines, Inc. |
1.43B |
1.09% |
|
|
|
|
|
76.52 |
5.05% |
76.58% |
26.79% |
|---|
| RCUS |
Arcus Biosciences, Inc. |
1.42B |
1.09% |
|
|
|
|
|
15.50 |
0.26% |
75.80% |
31.25% |
|---|
| IMCR |
Immunocore Holdings plc |
1.42B |
1.09% |
|
|
|
|
|
28.33 |
-0.33% |
68.43% |
46.26% |
|---|
| NVAX |
Novavax, Inc. |
1.39B |
1.07% |
|
|
|
|
|
8.70 |
0.23% |
161.26% |
55.22% |
|---|
| AUPH |
Aurinia Pharmaceuticals Inc. |
1.29B |
0.99% |
|
|
|
|
|
9.03 |
-0.11% |
71.96% |
35.43% |
|---|
| DAWN |
Day One Biopharmaceuticals, Inc. |
1.29B |
0.99% |
|
|
|
|
|
12.79 |
2.65% |
86.33% |
13.55% |
|---|
| NTLA |
Intellia Therapeutics, Inc. |
1.24B |
0.95% |
|
|
|
|
|
12.18 |
0.83% |
101.81% |
102.14% |
|---|
| PHVS |
Pharvaris N.V. |
1.06B |
0.81% |
|
|
|
|
|
19.57 |
2.95% |
N/A |
N/A |
|---|
| VIR |
Vir Biotechnology, Inc. |
1.01B |
0.78% |
|
|
|
|
|
7.34 |
-0.41% |
153.78% |
97.65% |
|---|
| REPL |
Replimune Group, Inc. |
941.00M |
0.72% |
|
|
|
|
|
12.49 |
4.00% |
219.38% |
10.27% |
|---|
| LQDA |
Liquidia Corporation |
939.47M |
0.72% |
|
|
|
|
|
11.10 |
4.82% |
76.98% |
40.06% |
|---|
| NUVB |
Nuvation Bio Inc. |
902.00M |
0.69% |
|
|
|
|
|
2.6800 |
-0.37% |
121.65% |
26.94% |
|---|
| AVBP |
ArriVent BioPharma, Inc. Common Stock |
879.16M |
0.67% |
|
|
|
|
|
26.09 |
1.72% |
N/A |
N/A |
|---|
| UPB |
Upstream Bio Inc |
|
0.67% |
|
|
|
|
|
|
|
|
|
|---|
| PRTA |
Prothena Corporation plc |
818.97M |
0.63% |
|
|
|
|
|
15.22 |
-4.93% |
175.67% |
51.87% |
|---|
| PLRX |
Pliant Therapeutics, Inc. |
803.88M |
0.62% |
|
|
|
|
|
13.21 |
-0.68% |
86.37% |
25.44% |
|---|
| AVXL |
Anavex Life Sciences Corp. |
731.79M |
0.56% |
|
|
|
|
|
8.63 |
1.89% |
151.38% |
61.68% |
|---|
| ERAS |
Erasca, Inc. |
718.13M |
0.55% |
|
|
|
|
|
2.5400 |
3.67% |
303.87% |
41.26% |
|---|
| IRWD |
Ironwood Pharmaceuticals, Inc. |
712.12M |
0.55% |
|
|
|
|
|
4.45 |
14.69% |
259.46% |
73.53% |
|---|
| DNTH |
Dianthus Therapeutics, Inc. |
704.41M |
0.54% |
|
|
|
|
|
23.80 |
3.30% |
135.70% |
43.75% |
|---|
| KROS |
Keros Therapeutics, Inc. |
689.84M |
0.53% |
|
|
|
|
|
17.03 |
0.65% |
101.60% |
63.62% |
|---|
| CRGX |
CARGO Therapeutics, Inc. Common Stock |
685.81M |
0.53% |
|
|
|
|
|
14.90 |
10.29% |
106.06% |
44.62% |
|---|
| IMNM |
Immunome, Inc. |
684.71M |
0.53% |
|
|
|
|
|
10.97 |
-0.99% |
105.57% |
45.41% |
|---|
| MBX |
MBX Biosciences Inc |
|
0.52% |
|
|
|
|
|
|
|
|
|
|---|
| RAPP |
Rapport Therapeutics Inc |
|
0.51% |
|
|
|
|
|
|
|
|
|
|---|
| STOK |
Stoke Therapeutics, Inc. |
618.65M |
0.47% |
|
|
|
|
|
11.68 |
3.36% |
116.26% |
23.27% |
|---|
| MLYS |
Mineralys Therapeutics, Inc. |
614.15M |
0.47% |
|
|
|
|
|
12.34 |
4.31% |
278.83% |
41.97% |
|---|
| AUTL |
Autolus Therapeutics plc |
609.41M |
0.47% |
|
|
|
|
|
2.2900 |
2.23% |
205.21% |
31.48% |
|---|
| CAPR |
Capricor Therapeutics, Inc. |
594.29M |
0.46% |
|
|
|
|
|
13.07 |
1.32% |
166.44% |
28.20% |
|---|
| FLGT |
Fulgent Genetics, Inc. |
560.96M |
0.43% |
|
|
|
|
|
18.34 |
-2.19% |
62.67% |
63.66% |
|---|
| ANNX |
Annexon, Inc. |
557.49M |
0.43% |
|
|
|
|
|
5.23 |
0.19% |
117.98% |
16.95% |
|---|
| SVRA |
Savara Inc. |
554.33M |
0.43% |
|
|
|
|
|
3.23 |
0.00% |
133.73% |
8.21% |
|---|
| ATXS |
Astria Therapeutics, Inc. |
539.51M |
0.41% |
|
|
|
|
|
9.56 |
1.16% |
165.59% |
15.45% |
|---|
| TRML |
Tourmaline Bio, Inc. |
529.52M |
0.41% |
|
|
|
|
|
20.65 |
1.52% |
110.99% |
58.93% |
|---|
| RNAC |
Cartesian Therapeutics, Inc. |
489.30M |
0.37% |
|
|
|
|
|
19.02 |
-1.30% |
588.62% |
N/A |
|---|
| TBPH |
Theravance Biopharma, Inc. |
471.58M |
0.36% |
|
|
|
|
|
9.59 |
-1.44% |
305.33% |
77.39% |
|---|
| CELC |
Celcuity Inc. |
462.63M |
0.36% |
|
|
|
|
|
12.46 |
3.83% |
195.39% |
62.72% |
|---|
| URGN |
UroGen Pharma Ltd. |
449.00M |
0.34% |
|
|
|
|
|
10.64 |
-0.65% |
269.35% |
19.08% |
|---|
| ANAB |
AnaptysBio, Inc. |
442.74M |
0.34% |
|
|
|
|
|
14.55 |
-3.00% |
86.10% |
8.72% |
|---|
| ARCT |
Arcturus Therapeutics Holdings Inc. |
419.31M |
0.32% |
|
|
|
|
|
15.48 |
4.31% |
66.94% |
64.32% |
|---|
| ZBIO |
ProShares UltraPro Short Nasdaq Biotechn... |
|
0.32% |
|
|
|
|
|
10.01 |
2.56% |
N/A |
N/A |
|---|
| AURA |
Aura Biosciences, Inc. |
409.60M |
0.31% |
|
|
|
|
|
8.20 |
1.11% |
353.69% |
12.13% |
|---|
| YMAB |
Y-mAbs Therapeutics, Inc. |
370.85M |
0.28% |
|
|
|
|
|
8.28 |
-3.38% |
135.85% |
34.36% |
|---|
| OLMA |
Olema Pharmaceuticals, Inc. |
349.52M |
0.27% |
|
|
|
|
|
6.10 |
5.35% |
123.31% |
98.39% |
|---|
| SLRN |
Acelyrin, Inc. |
316.03M |
0.24% |
|
|
|
|
|
3.15 |
-2.17% |
202.22% |
64.09% |
|---|
| RIGL |
Rigel Pharmaceuticals, Inc. |
301.04M |
0.23% |
|
|
|
|
|
17.09 |
-0.70% |
64.82% |
2.55% |
|---|
| FDMT |
4D Molecular Therapeutics, Inc. |
291.70M |
0.22% |
|
|
|
|
|
6.31 |
9.17% |
190.40% |
52.85% |
|---|
| ALDX |
Aldeyra Therapeutics, Inc. |
290.60M |
0.22% |
|
|
|
|
|
4.88 |
0.41% |
N/A |
N/A |
|---|
| VNDA |
Vanda Pharmaceuticals Inc. |
278.71M |
0.21% |
|
|
|
|
|
4.78 |
3.24% |
86.75% |
32.00% |
|---|
| AMLX |
Amylyx Pharmaceuticals, Inc. |
277.62M |
0.21% |
|
|
|
|
|
4.05 |
2.27% |
87.97% |
34.65% |
|---|
| CMPS |
COMPASS Pathways plc |
271.63M |
0.21% |
|
|
|
|
|
3.97 |
1.28% |
106.65% |
86.50% |
|---|
| ITOS |
iTeos Therapeutics, Inc. |
271.08M |
0.21% |
|
|
|
|
|
7.42 |
2.77% |
723.36% |
41.53% |
|---|
| ELDN |
Eledon Pharmaceuticals, Inc. |
260.46M |
0.20% |
|
|
|
|
|
4.36 |
3.32% |
193.55% |
45.06% |
|---|
| LRMR |
Larimar Therapeutics, Inc. |
255.86M |
0.20% |
|
|
|
|
|
4.01 |
0.75% |
211.85% |
64.43% |
|---|
| RZLT |
Rezolute, Inc. |
254.37M |
0.20% |
|
|
|
|
|
4.39 |
3.78% |
131.59% |
35.25% |
|---|
|
Cash and Equivalents |
|
0.19% |
|
|
|
|
|
|
|
|
|
|---|
| ZNTL |
Zentalis Pharmaceuticals, Inc. |
213.80M |
0.16% |
|
|
|
|
|
3.00 |
2.39% |
352.52% |
63.13% |
|---|
| MGNX |
MacroGenics, Inc. |
199.59M |
0.15% |
|
|
|
|
|
3.18 |
0.00% |
63.49% |
5.87% |
|---|
| ACRS |
Aclaris Therapeutics, Inc. |
194.29M |
0.15% |
|
|
|
|
|
2.7200 |
-1.81% |
172.85% |
0.77% |
|---|
| PROK |
ProKidney Corp. |
440.48M |
0.15% |
|
|
|
|
|
1.5100 |
3.42% |
344.36% |
45.36% |
|---|
| ALEC |
Alector, Inc. |
182.15M |
0.14% |
|
|
|
|
|
1.8600 |
4.49% |
400.60% |
24.10% |
|---|
| KYTX |
Kyverna Therapeutics, Inc. Common Stock |
172.69M |
0.13% |
|
|
|
|
|
4.00 |
3.36% |
634.61% |
35.20% |
|---|
| STRO |
Sutro Biopharma, Inc. |
155.02M |
0.12% |
|
|
|
|
|
1.8800 |
3.30% |
322.69% |
66.29% |
|---|
| ENTA |
Enanta Pharmaceuticals, Inc. |
133.10M |
0.10% |
|
|
|
|
|
6.28 |
7.17% |
231.56% |
103.26% |
|---|
| 1835589D |
Chinook Therapeutics Inc. |
|
N/A |
|
|
|
|
|
|
|
|
|
|---|