| KRYS |
Krystal Biotech, Inc. |
5.25B |
3.73% |
|
|
|
|
|
182.74 |
-3.45% |
42.54% |
30.56% |
|---|
| IMVT |
Immunovant, Inc. |
4.23B |
3.46% |
|
|
|
|
|
28.90 |
-0.62% |
54.29% |
23.93% |
|---|
| ALKS |
Alkermes plc |
4.58B |
3.20% |
|
|
|
|
|
27.83 |
0.32% |
36.88% |
52.75% |
|---|
| CRNX |
Crinetics Pharmaceuticals, Inc. |
4.22B |
2.83% |
|
|
|
|
|
52.77 |
-0.42% |
49.08% |
45.07% |
|---|
| RNA |
Avidity Biosciences, Inc. |
5.23B |
2.74% |
|
|
|
|
|
44.63 |
5.78% |
46.12% |
3.50% |
|---|
| ACLX |
Arcellx, Inc. |
4.33B |
2.65% |
|
|
|
|
|
80.55 |
3.28% |
49.77% |
35.22% |
|---|
| DNLI |
Denali Therapeutics Inc. |
4.40B |
2.53% |
|
|
|
|
|
30.76 |
0.26% |
98.27% |
57.54% |
|---|
| CORT |
Corcept Therapeutics Incorporated |
4.42B |
2.50% |
|
|
|
|
|
42.27 |
6.45% |
44.00% |
16.95% |
|---|
| FOLD |
Amicus Therapeutics, Inc. |
3.24B |
2.44% |
|
|
|
|
|
10.91 |
-2.59% |
50.56% |
21.26% |
|---|
| MRUS |
Merus N.V. |
3.37B |
2.35% |
|
|
|
|
|
49.42 |
-1.36% |
46.43% |
10.62% |
|---|
| XENE |
Xenon Pharmaceuticals Inc. |
3.04B |
2.12% |
|
|
|
|
|
40.09 |
0.00% |
51.60% |
27.92% |
|---|
| MLTX |
MoonLake Immunotherapeutics |
3.34B |
2.02% |
|
|
|
|
|
53.11 |
4.16% |
69.88% |
26.81% |
|---|
| CLDX |
Celldex Therapeutics, Inc. |
2.77B |
2.02% |
|
|
|
|
|
41.85 |
1.48% |
98.96% |
51.55% |
|---|
| IDYA |
IDEAYA Biosciences, Inc. |
2.94B |
1.99% |
|
|
|
|
|
34.75 |
-2.88% |
76.90% |
66.55% |
|---|
| ACAD |
ACADIA Pharmaceuticals Inc. |
2.71B |
1.89% |
|
|
|
|
|
16.33 |
0.43% |
32.02% |
0.01% |
|---|
| GERN |
Geron Corporation |
2.72B |
1.79% |
|
|
|
|
|
4.52 |
-0.66% |
44.34% |
-2.25% |
|---|
| CGON |
CG Oncology, Inc. Common stock |
2.49B |
1.76% |
|
|
|
|
|
37.06 |
-1.83% |
79.87% |
16.72% |
|---|
| AGIO |
Agios Pharmaceuticals, Inc. |
2.59B |
1.76% |
|
|
|
|
|
45.54 |
-0.33% |
65.65% |
75.33% |
|---|
| PTGX |
Protagonist Therapeutics, Inc. |
2.64B |
1.73% |
|
|
|
|
|
44.77 |
-0.31% |
127.91% |
42.43% |
|---|
| PTCT |
PTC Therapeutics, Inc. |
2.73B |
1.70% |
|
|
|
|
|
35.48 |
1.17% |
52.62% |
9.88% |
|---|
| VCEL |
Vericel Corporation |
2.27B |
1.61% |
|
|
|
|
|
46.35 |
4.58% |
42.47% |
38.80% |
|---|
| VRNA |
Verona Pharma plc |
2.45B |
1.54% |
|
|
|
|
|
29.23 |
0.14% |
70.24% |
7.35% |
|---|
| APGE |
Apogee Therapeutics, Inc. |
3.12B |
1.53% |
|
|
|
|
|
53.34 |
5.33% |
53.28% |
42.68% |
|---|
| VERA |
Vera Therapeutics, Inc. |
2.21B |
1.47% |
|
|
|
|
|
40.33 |
0.77% |
50.84% |
1.25% |
|---|
| NTLA |
Intellia Therapeutics, Inc. |
2.29B |
1.42% |
|
|
|
|
|
22.52 |
-0.13% |
67.43% |
43.97% |
|---|
| ZLAB |
Zai Lab Limited |
2.10B |
1.41% |
|
|
|
|
|
21.22 |
2.17% |
39.29% |
14.00% |
|---|
| MIRM |
Mirum Pharmaceuticals, Inc. |
1.81B |
1.38% |
|
|
|
|
|
37.90 |
-5.93% |
73.26% |
48.94% |
|---|
| KROS |
Keros Therapeutics, Inc. |
2.09B |
1.36% |
|
|
|
|
|
55.71 |
1.22% |
49.13% |
11.53% |
|---|
| GLPG |
Galapagos NV |
2.00B |
1.31% |
|
|
|
|
|
30.28 |
-0.92% |
51.59% |
39.40% |
|---|
| AKRO |
Akero Therapeutics, Inc. |
1.87B |
1.28% |
|
|
|
|
|
26.96 |
1.20% |
50.46% |
5.85% |
|---|
| SLNO |
Soleno Therapeutics, Inc. |
2.08B |
1.28% |
|
|
|
|
|
53.55 |
1.19% |
56.06% |
8.70% |
|---|
| NMRA |
Neumora Therapeutics, Inc. Common Stock |
1.95B |
1.21% |
|
|
|
|
|
12.21 |
4.09% |
167.17% |
43.62% |
|---|
| ARVN |
Arvinas, Inc. |
1.71B |
1.20% |
|
|
|
|
|
24.97 |
-1.38% |
74.07% |
21.88% |
|---|
| IMCR |
Immunocore Holdings plc |
1.72B |
1.19% |
|
|
|
|
|
34.44 |
1.59% |
62.55% |
47.76% |
|---|
| BCRX |
BioCryst Pharmaceuticals, Inc. |
1.65B |
1.18% |
|
|
|
|
|
7.96 |
0.51% |
50.17% |
8.08% |
|---|
| SNDX |
Syndax Pharmaceuticals, Inc. |
1.53B |
1.17% |
|
|
|
|
|
18.00 |
-0.33% |
117.62% |
31.96% |
|---|
| MNKD |
MannKind Corporation |
1.83B |
1.16% |
|
|
|
|
|
6.66 |
1.52% |
121.35% |
14.58% |
|---|
| EWTX |
Edgewise Therapeutics, Inc. |
1.79B |
1.15% |
|
|
|
|
|
19.07 |
5.50% |
206.23% |
70.73% |
|---|
| KURA |
Kura Oncology, Inc. |
1.55B |
1.06% |
|
|
|
|
|
20.26 |
0.50% |
105.03% |
28.51% |
|---|
| RCUS |
Arcus Biosciences, Inc. |
1.51B |
1.03% |
|
|
|
|
|
16.49 |
-1.43% |
166.57% |
64.64% |
|---|
| NAMS |
NewAmsterdam Pharma Company N.V. |
1.44B |
1.03% |
|
|
|
|
|
15.95 |
3.24% |
270.04% |
46.03% |
|---|
| DAWN |
Day One Biopharmaceuticals, Inc. |
1.21B |
0.89% |
|
|
|
|
|
13.79 |
0.22% |
98.04% |
15.16% |
|---|
| IRON |
Disc Medicine, Inc. |
1.42B |
0.87% |
|
|
|
|
|
47.65 |
0.63% |
69.48% |
25.78% |
|---|
| LBPH |
Longboard Pharmaceuticals, Inc. |
1.14B |
0.80% |
|
|
|
|
|
29.31 |
6.27% |
104.92% |
15.28% |
|---|
| SPRY |
ARS Pharmaceuticals, Inc. |
1.36B |
0.80% |
|
|
|
|
|
14.05 |
7.66% |
76.90% |
1.12% |
|---|
| PRTA |
Prothena Corporation plc |
1.16B |
0.78% |
|
|
|
|
|
21.48 |
-2.10% |
100.73% |
2.60% |
|---|
| COGT |
Cogent Biosciences, Inc. |
1.15B |
0.76% |
|
|
|
|
|
10.55 |
0.29% |
102.04% |
13.83% |
|---|
| TARS |
Tarsus Pharmaceuticals, Inc. |
1.24B |
0.73% |
|
|
|
|
|
32.55 |
4.83% |
93.34% |
49.92% |
|---|
| PHVS |
Pharvaris N.V. |
1.09B |
0.72% |
|
|
|
|
|
20.26 |
0.05% |
N/A |
N/A |
|---|
| PRAX |
Praxis Precision Medicines, Inc. |
1.05B |
0.71% |
|
|
|
|
|
59.38 |
2.88% |
88.32% |
20.48% |
|---|
| XNCR |
Xencor, Inc. |
1.46B |
0.71% |
|
|
|
|
|
20.85 |
-0.90% |
74.15% |
78.18% |
|---|
| ANAB |
AnaptysBio, Inc. |
1.10B |
0.71% |
|
|
|
|
|
36.57 |
-2.48% |
71.27% |
45.41% |
|---|
| AUPH |
Aurinia Pharmaceuticals Inc. |
1.01B |
0.70% |
|
|
|
|
|
7.08 |
-0.84% |
61.89% |
19.77% |
|---|
| AVBP |
ArriVent BioPharma, Inc. Common Stock |
792.29M |
0.63% |
|
|
|
|
|
23.59 |
-1.46% |
N/A |
N/A |
|---|
| VRDN |
Viridian Therapeutics, Inc. |
1.35B |
0.61% |
|
|
|
|
|
21.06 |
-0.57% |
66.42% |
17.86% |
|---|
| ETNB |
89bio, Inc. |
880.11M |
0.59% |
|
|
|
|
|
8.31 |
-0.48% |
103.62% |
43.03% |
|---|
| DNTH |
Dianthus Therapeutics, Inc. |
763.21M |
0.58% |
|
|
|
|
|
26.00 |
0.04% |
105.94% |
63.23% |
|---|
| PLRX |
Pliant Therapeutics, Inc. |
760.02M |
0.57% |
|
|
|
|
|
12.50 |
-0.79% |
143.56% |
61.66% |
|---|
| FDMT |
4D Molecular Therapeutics, Inc. |
874.13M |
0.56% |
|
|
|
|
|
16.82 |
4.08% |
76.13% |
44.02% |
|---|
| ERAS |
Erasca, Inc. |
816.44M |
0.55% |
|
|
|
|
|
2.8900 |
0.00% |
252.58% |
23.84% |
|---|
| CRGX |
CARGO Therapeutics, Inc. Common Stock |
1.11B |
0.53% |
|
|
|
|
|
24.20 |
3.73% |
N/A |
N/A |
|---|
| IRWD |
Ironwood Pharmaceuticals, Inc. |
722.02M |
0.52% |
|
|
|
|
|
4.52 |
0.89% |
346.42% |
85.75% |
|---|
| LQDA |
Liquidia Corporation |
825.05M |
0.49% |
|
|
|
|
|
9.91 |
1.33% |
62.23% |
18.33% |
|---|
| APLT |
Applied Therapeutics, Inc. |
901.54M |
0.47% |
|
|
|
|
|
7.85 |
68.82% |
129.98% |
16.13% |
|---|
| OLMA |
Olema Pharmaceuticals, Inc. |
733.58M |
0.47% |
|
|
|
|
|
12.81 |
4.40% |
121.10% |
31.16% |
|---|
| REPL |
Replimune Group, Inc. |
757.00M |
0.46% |
|
|
|
|
|
11.08 |
0.45% |
229.43% |
10.15% |
|---|
| FLGT |
Fulgent Genetics, Inc. |
694.10M |
0.46% |
|
|
|
|
|
22.91 |
0.70% |
39.16% |
45.70% |
|---|
| SVRA |
Savara Inc. |
730.83M |
0.44% |
|
|
|
|
|
4.44 |
0.23% |
323.86% |
2.77% |
|---|
| YMAB |
Y-mAbs Therapeutics, Inc. |
604.81M |
0.43% |
|
|
|
|
|
13.57 |
-5.17% |
126.64% |
12.00% |
|---|
| MLYS |
Mineralys Therapeutics, Inc. |
581.30M |
0.42% |
|
|
|
|
|
11.69 |
-2.42% |
509.45% |
12.13% |
|---|
| ITOS |
iTeos Therapeutics, Inc. |
423.29M |
0.39% |
|
|
|
|
|
11.59 |
-4.33% |
80.43% |
53.57% |
|---|
| CELC |
Celcuity Inc. |
555.82M |
0.39% |
|
|
|
|
|
15.01 |
0.20% |
200.69% |
60.41% |
|---|
| FULC |
Fulcrum Therapeutics, Inc. |
214.66M |
0.38% |
|
|
|
|
|
3.44 |
-1.43% |
101.93% |
50.88% |
|---|
| ANNX |
Annexon, Inc. |
732.18M |
0.37% |
|
|
|
|
|
6.93 |
-0.86% |
72.56% |
12.89% |
|---|
| ALLO |
Allogene Therapeutics, Inc. |
602.24M |
0.37% |
|
|
|
|
|
2.8800 |
0.00% |
139.31% |
48.59% |
|---|
| ARCT |
Arcturus Therapeutics Holdings Inc. |
555.72M |
0.36% |
|
|
|
|
|
20.55 |
-2.19% |
66.84% |
23.56% |
|---|
| URGN |
UroGen Pharma Ltd. |
551.69M |
0.35% |
|
|
|
|
|
13.10 |
2.02% |
275.03% |
28.95% |
|---|
| AVXL |
Anavex Life Sciences Corp. |
466.38M |
0.33% |
|
|
|
|
|
5.50 |
0.73% |
89.83% |
33.56% |
|---|
| CMPS |
COMPASS Pathways plc |
499.23M |
0.32% |
|
|
|
|
|
7.30 |
1.11% |
171.20% |
53.71% |
|---|
| ALT |
Altimmune, Inc. |
528.06M |
0.32% |
|
|
|
|
|
7.43 |
-1.85% |
105.76% |
15.81% |
|---|
| SLRN |
Acelyrin, Inc. |
459.12M |
0.32% |
|
|
|
|
|
4.60 |
5.02% |
228.12% |
50.43% |
|---|
| GHRS |
GH Research PLC |
415.70M |
0.31% |
|
|
|
|
|
7.99 |
-1.36% |
264.10% |
123.97% |
|---|
| ALEC |
Alector, Inc. |
548.89M |
0.31% |
|
|
|
|
|
5.64 |
0.00% |
241.98% |
65.90% |
|---|
| TRML |
Tourmaline Bio, Inc. |
538.47M |
0.29% |
|
|
|
|
|
21.00 |
8.58% |
120.51% |
44.31% |
|---|
| TBPH |
Theravance Biopharma, Inc. |
404.59M |
0.28% |
|
|
|
|
|
8.27 |
0.36% |
66.23% |
33.24% |
|---|
| AURA |
Aura Biosciences, Inc. |
473.74M |
0.27% |
|
|
|
|
|
9.55 |
-0.21% |
143.83% |
20.46% |
|---|
| ALDX |
Aldeyra Therapeutics, Inc. |
348.80M |
0.26% |
|
|
|
|
|
5.87 |
1.56% |
119.93% |
23.57% |
|---|
| STRO |
Sutro Biopharma, Inc. |
323.76M |
0.25% |
|
|
|
|
|
3.95 |
-1.50% |
480.15% |
48.49% |
|---|
| ANRO |
Alto Neuroscience, Inc. |
355.86M |
0.24% |
|
|
|
|
|
13.20 |
-3.93% |
N/A |
N/A |
|---|
| KYTX |
Kyverna Therapeutics, Inc. Common Stock |
284.77M |
0.23% |
|
|
|
|
|
6.60 |
-0.90% |
534.10% |
47.33% |
|---|
| INZY |
Inozyme Pharma, Inc. |
364.49M |
0.23% |
|
|
|
|
|
5.81 |
-0.34% |
922.41% |
17.88% |
|---|
| ACIU |
AC Immune SA |
361.84M |
0.22% |
|
|
|
|
|
3.63 |
4.91% |
162.26% |
53.60% |
|---|
| AVIR |
Atea Pharmaceuticals, Inc. |
336.84M |
0.21% |
|
|
|
|
|
3.99 |
-0.75% |
179.36% |
81.56% |
|---|
| VNDA |
Vanda Pharmaceuticals Inc. |
288.53M |
0.21% |
|
|
|
|
|
4.95 |
0.20% |
79.38% |
58.39% |
|---|
| ENTA |
Enanta Pharmaceuticals, Inc. |
241.34M |
0.18% |
|
|
|
|
|
11.39 |
-2.23% |
219.29% |
23.04% |
|---|
| INXB |
Inhibrx Biosciences Inc. |
|
0.16% |
|
|
|
|
|
|
|
|
|
|---|
| ZNTL |
Zentalis Pharmaceuticals, Inc. |
295.81M |
0.16% |
|
|
|
|
|
4.16 |
1.46% |
70.66% |
48.96% |
|---|
| PROK |
ProKidney Corp. |
692.32M |
0.11% |
|
|
|
|
|
2.3900 |
0.00% |
230.23% |
58.05% |
|---|
| HLVX |
HilleVax, Inc. |
90.11M |
0.06% |
|
|
|
|
|
1.8100 |
0.00% |
N/A |
N/A |
|---|
|
Cash and Equivalents |
|
0.05% |
|
|
|
|
|
|
|
|
|
|---|