| CRNX |
Crinetics Pharmaceuticals, Inc. |
3.47B |
3.68% |
|
|
|
|
|
37.46 |
1.63% |
70.01% |
42.91% |
|---|
| ALKS |
Alkermes plc |
5.74B |
3.65% |
|
|
|
|
|
35.32 |
-0.51% |
55.46% |
54.71% |
|---|
| AXSM |
Axsome Therapeutics, Inc. |
6.72B |
3.22% |
|
|
|
|
|
137.75 |
6.70% |
49.12% |
14.02% |
|---|
| VRNA |
Verona Pharma plc |
5.56B |
3.01% |
|
|
|
|
|
67.96 |
5.87% |
57.13% |
5.82% |
|---|
| PTCT |
PTC Therapeutics, Inc. |
3.91B |
2.77% |
|
|
|
|
|
50.69 |
0.62% |
48.14% |
18.88% |
|---|
| RNA |
Avidity Biosciences, Inc. |
3.71B |
2.73% |
|
|
|
|
|
31.12 |
-4.33% |
67.15% |
32.35% |
|---|
| RYTM |
Rhythm Pharmaceuticals, Inc. |
3.45B |
2.71% |
|
|
|
|
|
56.07 |
-2.89% |
54.39% |
34.17% |
|---|
| MLTX |
MoonLake Immunotherapeutics |
2.67B |
2.62% |
|
|
|
|
|
42.33 |
0.55% |
81.70% |
55.18% |
|---|
| XENE |
Xenon Pharmaceuticals Inc. |
3.03B |
2.30% |
|
|
|
|
|
39.73 |
0.89% |
55.26% |
36.00% |
|---|
| DNLI |
Denali Therapeutics Inc. |
2.98B |
2.28% |
|
|
|
|
|
20.73 |
-3.98% |
64.25% |
67.19% |
|---|
| ZLAB |
Zai Lab Limited |
3.68B |
2.27% |
|
|
|
|
|
33.78 |
9.00% |
123.26% |
31.64% |
|---|
| MRUS |
Merus N.V. |
3.24B |
2.25% |
|
|
|
|
|
47.37 |
-0.55% |
47.93% |
28.86% |
|---|
| FOLD |
Amicus Therapeutics, Inc. |
2.75B |
2.20% |
|
|
|
|
|
9.19 |
1.32% |
51.71% |
48.01% |
|---|
| ACAD |
ACADIA Pharmaceuticals Inc. |
3.32B |
2.18% |
|
|
|
|
|
19.95 |
-1.68% |
52.38% |
52.95% |
|---|
| VCEL |
Vericel Corporation |
2.57B |
2.14% |
|
|
|
|
|
52.00 |
-4.25% |
58.27% |
68.59% |
|---|
| VERA |
Vera Therapeutics, Inc. |
1.81B |
2.09% |
|
|
|
|
|
28.58 |
-3.48% |
65.71% |
41.74% |
|---|
| EWTX |
Edgewise Therapeutics, Inc. |
2.56B |
2.01% |
|
|
|
|
|
27.07 |
-0.11% |
89.13% |
32.58% |
|---|
| NAMS |
NewAmsterdam Pharma Company N.V. |
1.98B |
1.85% |
|
|
|
|
|
18.57 |
-2.26% |
113.43% |
11.89% |
|---|
| PTGX |
Protagonist Therapeutics, Inc. |
2.31B |
1.80% |
|
|
|
|
|
38.75 |
0.68% |
68.70% |
84.70% |
|---|
| IDYA |
IDEAYA Biosciences, Inc. |
1.91B |
1.69% |
|
|
|
|
|
21.85 |
0.55% |
142.62% |
50.52% |
|---|
| TARS |
Tarsus Pharmaceuticals, Inc. |
1.83B |
1.64% |
|
|
|
|
|
47.84 |
-1.81% |
72.63% |
39.34% |
|---|
| APGE |
Apogee Therapeutics, Inc. |
2.02B |
1.58% |
|
|
|
|
|
34.55 |
1.77% |
66.75% |
58.62% |
|---|
| MIRM |
Mirum Pharmaceuticals, Inc. |
2.52B |
1.55% |
|
|
|
|
|
52.45 |
-1.34% |
49.91% |
47.78% |
|---|
| AKRO |
Akero Therapeutics, Inc. |
3.89B |
1.53% |
|
|
|
|
|
51.84 |
2.49% |
73.43% |
9.65% |
|---|
| CGON |
CG Oncology, Inc. Common stock |
2.12B |
1.51% |
|
|
|
|
|
27.85 |
-1.31% |
102.73% |
25.34% |
|---|
| AGIO |
Agios Pharmaceuticals, Inc. |
2.02B |
1.48% |
|
|
|
|
|
35.22 |
4.36% |
67.83% |
61.09% |
|---|
| IRON |
Disc Medicine, Inc. |
1.87B |
1.44% |
|
|
|
|
|
54.53 |
0.33% |
76.09% |
3.77% |
|---|
| GLPG |
Galapagos NV |
1.76B |
1.41% |
|
|
|
|
|
26.74 |
0.04% |
72.56% |
32.06% |
|---|
| MNKD |
MannKind Corporation |
1.59B |
1.41% |
|
|
|
|
|
5.76 |
1.77% |
97.36% |
67.13% |
|---|
| NMRA |
Neumora Therapeutics, Inc. Common Stock |
290.81M |
1.40% |
|
|
|
|
|
1.8000 |
5.26% |
105.51% |
22.06% |
|---|
| CLDX |
Celldex Therapeutics, Inc. |
1.49B |
1.31% |
|
|
|
|
|
22.46 |
-0.58% |
48.11% |
8.05% |
|---|
| XNCR |
Xencor, Inc. |
1.10B |
1.30% |
|
|
|
|
|
15.74 |
-0.32% |
81.40% |
45.37% |
|---|
| BCRX |
BioCryst Pharmaceuticals, Inc. |
1.91B |
1.22% |
|
|
|
|
|
9.21 |
-1.92% |
50.70% |
31.73% |
|---|
| VRDN |
Viridian Therapeutics, Inc. |
1.29B |
1.21% |
|
|
|
|
|
16.27 |
-2.11% |
48.83% |
22.20% |
|---|
| GPCR |
Structure Therapeutics Inc. |
1.36B |
1.19% |
|
|
|
|
|
23.77 |
1.60% |
82.10% |
21.09% |
|---|
| IMCR |
Immunocore Holdings plc |
1.50B |
1.14% |
|
|
|
|
|
29.92 |
0.17% |
80.23% |
74.51% |
|---|
| PRAX |
Praxis Precision Medicines, Inc. |
1.39B |
1.11% |
|
|
|
|
|
74.49 |
-6.35% |
167.62% |
93.03% |
|---|
| RCUS |
Arcus Biosciences, Inc. |
1.16B |
1.07% |
|
|
|
|
|
11.07 |
3.07% |
286.49% |
36.95% |
|---|
| AUPH |
Aurinia Pharmaceuticals Inc. |
1.14B |
1.03% |
|
|
|
|
|
7.93 |
1.28% |
72.96% |
54.58% |
|---|
| NVAX |
Novavax, Inc. |
1.28B |
1.00% |
|
|
|
|
|
7.99 |
0.88% |
110.93% |
53.06% |
|---|
| DAWN |
Day One Biopharmaceuticals, Inc. |
1.25B |
0.99% |
|
|
|
|
|
12.43 |
1.64% |
62.90% |
22.19% |
|---|
| NTLA |
Intellia Therapeutics, Inc. |
1.24B |
0.91% |
|
|
|
|
|
12.17 |
-0.65% |
84.48% |
67.28% |
|---|
| PHVS |
Pharvaris N.V. |
890.59M |
0.81% |
|
|
|
|
|
16.49 |
-0.06% |
N/A |
N/A |
|---|
| VIR |
Vir Biotechnology, Inc. |
1.32B |
0.79% |
|
|
|
|
|
9.57 |
-2.35% |
70.90% |
60.24% |
|---|
| LQDA |
Liquidia Corporation |
1.36B |
0.76% |
|
|
|
|
|
16.12 |
-2.33% |
66.08% |
22.39% |
|---|
| AVXL |
Anavex Life Sciences Corp. |
710.29M |
0.73% |
|
|
|
|
|
8.35 |
-3.80% |
98.87% |
24.74% |
|---|
| REPL |
Replimune Group, Inc. |
1.08B |
0.73% |
|
|
|
|
|
13.98 |
-2.31% |
122.01% |
11.97% |
|---|
| UPB |
Upstream Bio Inc. |
|
0.72% |
|
|
|
|
|
|
|
|
|
|---|
| AVBP |
ArriVent BioPharma, Inc. Common Stock |
912.18M |
0.71% |
|
|
|
|
|
27.07 |
-1.17% |
N/A |
N/A |
|---|
| NUVB |
Nuvation Bio Inc. |
743.81M |
0.69% |
|
|
|
|
|
2.2100 |
-2.64% |
256.22% |
48.20% |
|---|
| PRTA |
Prothena Corporation plc |
837.26M |
0.63% |
|
|
|
|
|
15.56 |
2.03% |
80.41% |
13.11% |
|---|
| PLRX |
Pliant Therapeutics, Inc. |
187.43M |
0.61% |
|
|
|
|
|
3.08 |
2.33% |
117.25% |
49.57% |
|---|
| ERAS |
Erasca, Inc. |
398.65M |
0.57% |
|
|
|
|
|
1.4100 |
-3.42% |
364.07% |
47.07% |
|---|
| IRWD |
Ironwood Pharmaceuticals, Inc. |
290.45M |
0.55% |
|
|
|
|
|
1.8150 |
-4.47% |
191.36% |
37.44% |
|---|
| RAPP |
Rapport Therapeutics Inc. |
|
0.53% |
|
|
|
|
|
|
|
|
|
|---|
| IMNM |
Immunome, Inc. |
806.11M |
0.50% |
|
|
|
|
|
9.52 |
-5.84% |
145.43% |
59.22% |
|---|
| DNTH |
Dianthus Therapeutics, Inc. |
700.56M |
0.50% |
|
|
|
|
|
23.67 |
-0.13% |
101.76% |
28.96% |
|---|
| CRGX |
CARGO Therapeutics, Inc. Common Stock |
173.52M |
0.50% |
|
|
|
|
|
3.77 |
2.17% |
116.77% |
46.62% |
|---|
| KROS |
Keros Therapeutics, Inc. |
446.39M |
0.50% |
|
|
|
|
|
11.02 |
-0.09% |
87.60% |
64.75% |
|---|
| CAPR |
Capricor Therapeutics, Inc. |
682.05M |
0.49% |
|
|
|
|
|
15.00 |
-0.99% |
128.94% |
65.43% |
|---|
| MLYS |
Mineralys Therapeutics, Inc. |
475.79M |
0.49% |
|
|
|
|
|
9.56 |
0.31% |
399.28% |
87.03% |
|---|
| MBX |
MBX Biosciences Inc. |
|
0.47% |
|
|
|
|
|
|
|
|
|
|---|
| AUTL |
Autolus Therapeutics plc |
518.93M |
0.46% |
|
|
|
|
|
1.9500 |
0.00% |
378.96% |
33.34% |
|---|
| STOK |
Stoke Therapeutics, Inc. |
441.22M |
0.45% |
|
|
|
|
|
8.33 |
-4.69% |
405.70% |
44.05% |
|---|
| FLGT |
Fulgent Genetics, Inc. |
503.46M |
0.44% |
|
|
|
|
|
16.46 |
-1.02% |
88.61% |
74.99% |
|---|
| ANNX |
Annexon, Inc. |
299.53M |
0.43% |
|
|
|
|
|
2.8100 |
-0.71% |
222.49% |
29.61% |
|---|
| SVRA |
Savara Inc. |
461.66M |
0.41% |
|
|
|
|
|
2.6900 |
0.00% |
110.17% |
14.12% |
|---|
| TRML |
Tourmaline Bio, Inc. |
313.10M |
0.40% |
|
|
|
|
|
12.21 |
-1.29% |
217.10% |
95.49% |
|---|
| ATXS |
Astria Therapeutics, Inc. |
384.32M |
0.39% |
|
|
|
|
|
6.81 |
-0.15% |
104.44% |
36.30% |
|---|
| CELC |
Celcuity Inc. |
488.25M |
0.38% |
|
|
|
|
|
13.15 |
0.15% |
192.76% |
45.60% |
|---|
| RNAC |
Cartesian Therapeutics, Inc. |
494.95M |
0.37% |
|
|
|
|
|
19.24 |
-1.89% |
588.62% |
N/A |
|---|
| TBPH |
Theravance Biopharma, Inc. |
458.06M |
0.37% |
|
|
|
|
|
9.32 |
-3.57% |
309.67% |
42.15% |
|---|
| ARCT |
Arcturus Therapeutics Holdings Inc. |
481.34M |
0.35% |
|
|
|
|
|
17.77 |
5.02% |
84.60% |
49.44% |
|---|
| URGN |
UroGen Pharma Ltd. |
425.37M |
0.35% |
|
|
|
|
|
10.08 |
-5.88% |
386.64% |
69.21% |
|---|
| AURA |
Aura Biosciences, Inc. |
375.14M |
0.32% |
|
|
|
|
|
7.51 |
-1.57% |
196.57% |
13.60% |
|---|
| ANAB |
AnaptysBio, Inc. |
565.67M |
0.32% |
|
|
|
|
|
18.59 |
-1.48% |
164.29% |
15.57% |
|---|
| ZBIO |
ProShares UltraPro Short Nasdaq Biotechn... |
|
0.29% |
|
|
|
|
|
7.83 |
0.26% |
N/A |
N/A |
|---|
| YMAB |
Y-mAbs Therapeutics, Inc. |
256.19M |
0.27% |
|
|
|
|
|
5.72 |
-5.30% |
299.13% |
47.42% |
|---|
| OLMA |
Olema Pharmaceuticals, Inc. |
340.98M |
0.25% |
|
|
|
|
|
4.99 |
-1.77% |
252.67% |
52.79% |
|---|
| SLRN |
Acelyrin, Inc. |
260.85M |
0.24% |
|
|
|
|
|
2.6000 |
19.82% |
333.04% |
42.40% |
|---|
| ALDX |
Aldeyra Therapeutics, Inc. |
398.39M |
0.23% |
|
|
|
|
|
6.69 |
-0.45% |
257.76% |
20.55% |
|---|
| RIGL |
Rigel Pharmaceuticals, Inc. |
353.89M |
0.23% |
|
|
|
|
|
20.09 |
-3.55% |
88.68% |
4.79% |
|---|
| RZLT |
Rezolute, Inc. |
274.23M |
0.22% |
|
|
|
|
|
4.53 |
-2.16% |
300.54% |
47.87% |
|---|
| VNDA |
Vanda Pharmaceuticals Inc. |
258.34M |
0.22% |
|
|
|
|
|
4.43 |
-1.34% |
86.92% |
44.11% |
|---|
| ITOS |
iTeos Therapeutics, Inc. |
270.72M |
0.21% |
|
|
|
|
|
7.41 |
-0.94% |
641.47% |
19.90% |
|---|
| AMLX |
Amylyx Pharmaceuticals, Inc. |
282.78M |
0.21% |
|
|
|
|
|
3.30 |
-6.25% |
307.72% |
37.85% |
|---|
| CMPS |
COMPASS Pathways plc |
288.05M |
0.20% |
|
|
|
|
|
4.21 |
-7.27% |
216.18% |
94.70% |
|---|
| LRMR |
Larimar Therapeutics, Inc. |
203.54M |
0.20% |
|
|
|
|
|
3.19 |
-2.45% |
265.15% |
64.07% |
|---|
| ELDN |
Eledon Pharmaceuticals, Inc. |
256.28M |
0.19% |
|
|
|
|
|
4.29 |
-1.15% |
161.70% |
70.48% |
|---|
| FDMT |
4D Molecular Therapeutics, Inc. |
214.50M |
0.19% |
|
|
|
|
|
4.64 |
-0.64% |
245.06% |
85.47% |
|---|
|
Cash and Equivalents |
|
0.19% |
|
|
|
|
|
|
|
|
|
|---|
| PROK |
ProKidney Corp. |
437.56M |
0.18% |
|
|
|
|
|
1.5000 |
-1.32% |
595.08% |
62.54% |
|---|
| ZNTL |
Zentalis Pharmaceuticals, Inc. |
165.34M |
0.16% |
|
|
|
|
|
2.3200 |
-6.07% |
370.78% |
33.60% |
|---|
| MGNX |
MacroGenics, Inc. |
173.23M |
0.16% |
|
|
|
|
|
2.7600 |
-4.17% |
120.94% |
20.16% |
|---|
| ACRS |
Aclaris Therapeutics, Inc. |
239.72M |
0.14% |
|
|
|
|
|
2.2400 |
-3.03% |
94.58% |
21.22% |
|---|
| ALEC |
Alector, Inc. |
183.13M |
0.13% |
|
|
|
|
|
1.8700 |
0.54% |
666.34% |
23.18% |
|---|
| KYTX |
Kyverna Therapeutics, Inc. Common Stock |
120.02M |
0.12% |
|
|
|
|
|
2.7800 |
-2.11% |
634.61% |
41.31% |
|---|
| STRO |
Sutro Biopharma, Inc. |
145.95M |
0.12% |
|
|
|
|
|
1.7700 |
-3.28% |
579.44% |
85.22% |
|---|
| ENTA |
Enanta Pharmaceuticals, Inc. |
171.30M |
0.10% |
|
|
|
|
|
8.03 |
-4.18% |
220.08% |
29.15% |
|---|
| 1835589D |
Chinook Therapeutics Inc. |
|
N/A |
|
|
|
|
|
|
|
|
|
|---|