| CRNX |
Crinetics Pharmaceuticals, Inc. |
3.12B |
3.68% |
|
|
|
|
|
33.54 |
-3.43% |
70.01% |
19.32% |
|---|
| ALKS |
Alkermes plc |
5.37B |
3.65% |
|
|
|
|
|
33.02 |
-0.57% |
55.46% |
64.86% |
|---|
| AXSM |
Axsome Therapeutics, Inc. |
5.69B |
3.22% |
|
|
|
|
|
116.63 |
-1.60% |
49.12% |
16.06% |
|---|
| VRNA |
Verona Pharma plc |
5.37B |
3.01% |
|
|
|
|
|
63.49 |
1.26% |
57.13% |
12.25% |
|---|
| PTCT |
PTC Therapeutics, Inc. |
4.02B |
2.77% |
|
|
|
|
|
50.96 |
-6.05% |
48.14% |
44.19% |
|---|
| RNA |
Avidity Biosciences, Inc. |
3.55B |
2.73% |
|
|
|
|
|
29.52 |
-6.58% |
67.15% |
33.14% |
|---|
| RYTM |
Rhythm Pharmaceuticals, Inc. |
3.35B |
2.71% |
|
|
|
|
|
52.97 |
-3.34% |
54.39% |
71.71% |
|---|
| MLTX |
MoonLake Immunotherapeutics |
2.47B |
2.62% |
|
|
|
|
|
39.07 |
-1.98% |
81.70% |
44.08% |
|---|
| XENE |
Xenon Pharmaceuticals Inc. |
2.57B |
2.30% |
|
|
|
|
|
33.55 |
-2.07% |
55.26% |
88.83% |
|---|
| DNLI |
Denali Therapeutics Inc. |
1.97B |
2.28% |
|
|
|
|
|
13.60 |
-8.02% |
64.25% |
84.06% |
|---|
| ZLAB |
Zai Lab Limited |
391.31M |
2.27% |
|
|
|
|
|
36.14 |
-3.08% |
123.26% |
20.27% |
|---|
| MRUS |
Merus N.V. |
2.91B |
2.25% |
|
|
|
|
|
42.09 |
-5.65% |
47.93% |
18.66% |
|---|
| FOLD |
Amicus Therapeutics, Inc. |
2.51B |
2.20% |
|
|
|
|
|
8.16 |
-3.20% |
51.71% |
78.80% |
|---|
| ACAD |
ACADIA Pharmaceuticals Inc. |
2.77B |
2.18% |
|
|
|
|
|
16.61 |
-2.69% |
52.38% |
68.59% |
|---|
| VCEL |
Vericel Corporation |
2.24B |
2.14% |
|
|
|
|
|
44.62 |
0.27% |
58.27% |
94.35% |
|---|
| VERA |
Vera Therapeutics, Inc. |
1.53B |
2.09% |
|
|
|
|
|
24.02 |
-9.80% |
65.71% |
127.00% |
|---|
| EWTX |
Edgewise Therapeutics, Inc. |
2.09B |
2.01% |
|
|
|
|
|
22.00 |
-5.46% |
89.13% |
20.69% |
|---|
| NAMS |
NewAmsterdam Pharma Company N.V. |
2.25B |
1.85% |
|
|
|
|
|
20.47 |
-5.93% |
113.43% |
14.01% |
|---|
| PTGX |
Protagonist Therapeutics, Inc. |
2.97B |
1.80% |
|
|
|
|
|
48.36 |
-1.06% |
68.70% |
-0.14% |
|---|
| IDYA |
IDEAYA Biosciences, Inc. |
1.43B |
1.69% |
|
|
|
|
|
16.38 |
-3.93% |
142.62% |
64.67% |
|---|
| TARS |
Tarsus Pharmaceuticals, Inc. |
2.14B |
1.64% |
|
|
|
|
|
51.37 |
-0.72% |
72.63% |
15.55% |
|---|
| APGE |
Apogee Therapeutics, Inc. |
2.22B |
1.58% |
|
|
|
|
|
37.36 |
-5.94% |
66.75% |
42.99% |
|---|
| MIRM |
Mirum Pharmaceuticals, Inc. |
2.21B |
1.55% |
|
|
|
|
|
45.05 |
-2.04% |
49.91% |
30.81% |
|---|
| AKRO |
Akero Therapeutics, Inc. |
3.22B |
1.53% |
|
|
|
|
|
40.48 |
-5.24% |
73.43% |
14.24% |
|---|
| CGON |
CG Oncology, Inc. Common stock |
1.88B |
1.51% |
|
|
|
|
|
24.49 |
-7.31% |
102.73% |
13.47% |
|---|
| AGIO |
Agios Pharmaceuticals, Inc. |
1.68B |
1.48% |
|
|
|
|
|
29.30 |
-3.24% |
67.83% |
43.10% |
|---|
| IRON |
Disc Medicine, Inc. |
1.72B |
1.44% |
|
|
|
|
|
49.64 |
-5.19% |
76.09% |
37.96% |
|---|
| GLPG |
Galapagos NV |
1.66B |
1.41% |
|
|
|
|
|
25.12 |
-1.34% |
72.56% |
62.37% |
|---|
| MNKD |
MannKind Corporation |
1.53B |
1.41% |
|
|
|
|
|
5.03 |
0.00% |
67.81% |
46.35% |
|---|
| NMRA |
Neumora Therapeutics, Inc. Common Stock |
161.98M |
1.40% |
|
|
|
|
|
1.0000 |
-2.91% |
105.51% |
48.00% |
|---|
| CLDX |
Celldex Therapeutics, Inc. |
1.20B |
1.31% |
|
|
|
|
|
18.15 |
-8.93% |
48.11% |
83.12% |
|---|
| XNCR |
Xencor, Inc. |
749.71M |
1.30% |
|
|
|
|
|
10.64 |
-5.25% |
81.40% |
84.12% |
|---|
| BCRX |
BioCryst Pharmaceuticals, Inc. |
1.57B |
1.22% |
|
|
|
|
|
7.50 |
-4.58% |
50.70% |
27.56% |
|---|
| VRDN |
Viridian Therapeutics, Inc. |
1.10B |
1.21% |
|
|
|
|
|
13.48 |
-6.65% |
48.83% |
34.28% |
|---|
| GPCR |
Structure Therapeutics Inc. |
330.54M |
1.19% |
|
|
|
|
|
17.31 |
-12.44% |
82.10% |
44.28% |
|---|
| IMCR |
Immunocore Holdings plc |
1.49B |
1.14% |
|
|
|
|
|
29.67 |
0.30% |
80.23% |
23.58% |
|---|
| PRAX |
Praxis Precision Medicines, Inc. |
763.58M |
1.11% |
|
|
|
|
|
37.87 |
-2.04% |
167.62% |
28.28% |
|---|
| RCUS |
Arcus Biosciences, Inc. |
830.85M |
1.07% |
|
|
|
|
|
7.85 |
-3.92% |
286.49% |
61.96% |
|---|
| AUPH |
Aurinia Pharmaceuticals Inc. |
1.10B |
1.03% |
|
|
|
|
|
8.04 |
-3.02% |
72.96% |
34.02% |
|---|
| NVAX |
Novavax, Inc. |
1.03B |
1.00% |
|
|
|
|
|
6.41 |
-8.43% |
61.09% |
20.52% |
|---|
| DAWN |
Day One Biopharmaceuticals, Inc. |
803.75M |
0.99% |
|
|
|
|
|
7.93 |
-1.73% |
62.90% |
40.88% |
|---|
| NTLA |
Intellia Therapeutics, Inc. |
736.01M |
0.91% |
|
|
|
|
|
7.11 |
-11.90% |
84.48% |
60.48% |
|---|
| PHVS |
Pharvaris N.V. |
847.92M |
0.81% |
|
|
|
|
|
15.70 |
-0.63% |
N/A |
N/A |
|---|
| VIR |
Vir Biotechnology, Inc. |
888.69M |
0.79% |
|
|
|
|
|
6.48 |
-3.28% |
70.90% |
64.46% |
|---|
| LQDA |
Liquidia Corporation |
1.26B |
0.76% |
|
|
|
|
|
14.75 |
-2.25% |
66.08% |
10.19% |
|---|
| AVXL |
Anavex Life Sciences Corp. |
729.85M |
0.73% |
|
|
|
|
|
8.58 |
-1.61% |
98.87% |
22.58% |
|---|
| REPL |
Replimune Group, Inc. |
750.89M |
0.73% |
|
|
|
|
|
9.75 |
-6.16% |
122.01% |
13.49% |
|---|
| UPB |
Upstream Bio Inc. |
|
0.72% |
|
|
|
|
|
|
|
|
|
|---|
| AVBP |
ArriVent BioPharma, Inc. Common Stock |
628.96M |
0.71% |
|
|
|
|
|
18.49 |
-2.43% |
N/A |
N/A |
|---|
| NUVB |
Nuvation Bio Inc. |
594.32M |
0.69% |
|
|
|
|
|
1.7600 |
-3.30% |
256.22% |
64.12% |
|---|
| PRTA |
Prothena Corporation plc |
666.11M |
0.63% |
|
|
|
|
|
12.38 |
-5.82% |
80.41% |
29.11% |
|---|
| PLRX |
Pliant Therapeutics, Inc. |
82.67M |
0.61% |
|
|
|
|
|
1.3500 |
-8.16% |
117.25% |
44.72% |
|---|
| ERAS |
Erasca, Inc. |
388.07M |
0.57% |
|
|
|
|
|
1.3700 |
-9.87% |
364.07% |
63.53% |
|---|
| IRWD |
Ironwood Pharmaceuticals, Inc. |
235.24M |
0.55% |
|
|
|
|
|
1.4700 |
4.26% |
191.36% |
23.63% |
|---|
| RAPP |
Rapport Therapeutics Inc. |
|
0.53% |
|
|
|
|
|
|
|
|
|
|---|
| IMNM |
Immunome, Inc. |
585.18M |
0.50% |
|
|
|
|
|
6.73 |
-3.72% |
145.43% |
50.19% |
|---|
| DNTH |
Dianthus Therapeutics, Inc. |
582.75M |
0.50% |
|
|
|
|
|
18.14 |
-9.25% |
101.76% |
26.65% |
|---|
| CRGX |
CARGO Therapeutics, Inc. Common Stock |
187.43M |
0.50% |
|
|
|
|
|
4.07 |
-2.63% |
116.77% |
86.35% |
|---|
| KROS |
Keros Therapeutics, Inc. |
413.33M |
0.50% |
|
|
|
|
|
10.19 |
-5.56% |
87.60% |
39.62% |
|---|
| CAPR |
Capricor Therapeutics, Inc. |
433.47M |
0.49% |
|
|
|
|
|
9.49 |
-17.48% |
128.94% |
33.85% |
|---|
| MLYS |
Mineralys Therapeutics, Inc. |
997.02M |
0.49% |
|
|
|
|
|
15.88 |
8.32% |
399.28% |
12.95% |
|---|
| MBX |
MBX Biosciences Inc. |
|
0.47% |
|
|
|
|
|
|
|
|
|
|---|
| AUTL |
Autolus Therapeutics plc |
412.49M |
0.46% |
|
|
|
|
|
1.5500 |
-6.63% |
378.96% |
11.53% |
|---|
| STOK |
Stoke Therapeutics, Inc. |
352.23M |
0.45% |
|
|
|
|
|
6.65 |
-7.77% |
405.70% |
78.43% |
|---|
| FLGT |
Fulgent Genetics, Inc. |
521.63M |
0.44% |
|
|
|
|
|
16.90 |
-0.88% |
88.61% |
53.29% |
|---|
| ANNX |
Annexon, Inc. |
211.74M |
0.43% |
|
|
|
|
|
1.9300 |
-14.22% |
222.49% |
61.11% |
|---|
| SVRA |
Savara Inc. |
475.38M |
0.41% |
|
|
|
|
|
2.7700 |
-4.81% |
110.17% |
9.55% |
|---|
| TRML |
Tourmaline Bio, Inc. |
390.67M |
0.40% |
|
|
|
|
|
15.21 |
-8.65% |
217.10% |
43.34% |
|---|
| ATXS |
Astria Therapeutics, Inc. |
301.36M |
0.39% |
|
|
|
|
|
5.34 |
-6.32% |
104.44% |
69.78% |
|---|
| CELC |
Celcuity Inc. |
375.38M |
0.38% |
|
|
|
|
|
10.11 |
-1.27% |
192.76% |
79.36% |
|---|
| RNAC |
Cartesian Therapeutics, Inc. |
341.46M |
0.37% |
|
|
|
|
|
13.18 |
-9.35% |
588.62% |
N/A |
|---|
| TBPH |
Theravance Biopharma, Inc. |
441.77M |
0.37% |
|
|
|
|
|
8.93 |
-3.25% |
309.67% |
21.22% |
|---|
| ARCT |
Arcturus Therapeutics Holdings Inc. |
287.20M |
0.35% |
|
|
|
|
|
10.59 |
-8.55% |
84.60% |
88.29% |
|---|
| URGN |
UroGen Pharma Ltd. |
509.80M |
0.35% |
|
|
|
|
|
11.06 |
-1.25% |
386.64% |
35.04% |
|---|
| AURA |
Aura Biosciences, Inc. |
294.32M |
0.32% |
|
|
|
|
|
5.86 |
-7.57% |
196.57% |
11.79% |
|---|
| ANAB |
AnaptysBio, Inc. |
570.10M |
0.32% |
|
|
|
|
|
18.59 |
-1.90% |
164.29% |
22.07% |
|---|
| ZBIO |
ProShares UltraPro Short Nasdaq Biotechn... |
|
0.29% |
|
|
|
|
|
7.90 |
-3.30% |
N/A |
N/A |
|---|
| YMAB |
Y-mAbs Therapeutics, Inc. |
200.32M |
0.27% |
|
|
|
|
|
4.43 |
-7.90% |
299.13% |
51.15% |
|---|
| OLMA |
Olema Pharmaceuticals, Inc. |
256.93M |
0.25% |
|
|
|
|
|
3.76 |
-8.52% |
252.67% |
44.43% |
|---|
| SLRN |
Acelyrin, Inc. |
248.75M |
0.24% |
|
|
|
|
|
2.4700 |
-5.00% |
333.04% |
41.28% |
|---|
| ALDX |
Aldeyra Therapeutics, Inc. |
343.33M |
0.23% |
|
|
|
|
|
5.75 |
-13.79% |
257.76% |
68.60% |
|---|
| RIGL |
Rigel Pharmaceuticals, Inc. |
321.36M |
0.23% |
|
|
|
|
|
17.99 |
0.62% |
88.68% |
6.53% |
|---|
| RZLT |
Rezolute, Inc. |
175.55M |
0.22% |
|
|
|
|
|
2.9000 |
-1.02% |
300.54% |
45.29% |
|---|
| VNDA |
Vanda Pharmaceuticals Inc. |
267.67M |
0.22% |
|
|
|
|
|
4.59 |
-2.13% |
86.92% |
28.46% |
|---|
| ITOS |
iTeos Therapeutics, Inc. |
228.02M |
0.21% |
|
|
|
|
|
5.97 |
-5.54% |
641.47% |
50.13% |
|---|
| AMLX |
Amylyx Pharmaceuticals, Inc. |
313.65M |
0.21% |
|
|
|
|
|
3.54 |
-3.28% |
307.72% |
48.75% |
|---|
| CMPS |
COMPASS Pathways plc |
196.06M |
0.20% |
|
|
|
|
|
2.8600 |
-2.72% |
216.18% |
69.12% |
|---|
| LRMR |
Larimar Therapeutics, Inc. |
137.66M |
0.20% |
|
|
|
|
|
2.1500 |
-8.51% |
265.15% |
52.65% |
|---|
| ELDN |
Eledon Pharmaceuticals, Inc. |
203.00M |
0.19% |
|
|
|
|
|
3.39 |
1.19% |
161.70% |
41.75% |
|---|
| FDMT |
4D Molecular Therapeutics, Inc. |
149.56M |
0.19% |
|
|
|
|
|
3.23 |
-11.02% |
245.06% |
63.09% |
|---|
|
Cash and Equivalents |
|
0.19% |
|
|
|
|
|
|
|
|
|
|---|
| PROK |
ProKidney Corp. |
256.46M |
0.18% |
|
|
|
|
|
0.8762 |
-3.71% |
595.08% |
62.54% |
|---|
| ZNTL |
Zentalis Pharmaceuticals, Inc. |
114.18M |
0.16% |
|
|
|
|
|
1.5900 |
-12.15% |
370.78% |
44.39% |
|---|
| MGNX |
MacroGenics, Inc. |
80.12M |
0.16% |
|
|
|
|
|
1.2700 |
0.79% |
120.94% |
26.81% |
|---|
| ACRS |
Aclaris Therapeutics, Inc. |
165.12M |
0.14% |
|
|
|
|
|
1.5300 |
-3.77% |
94.58% |
54.21% |
|---|
| ALEC |
Alector, Inc. |
121.88M |
0.13% |
|
|
|
|
|
1.2300 |
-4.65% |
666.34% |
19.90% |
|---|
| KYTX |
Kyverna Therapeutics, Inc. |
83.40M |
0.12% |
|
|
|
|
|
1.9300 |
-3.50% |
634.61% |
46.90% |
|---|
| STRO |
Sutro Biopharma, Inc. |
54.50M |
0.12% |
|
|
|
|
|
0.6506 |
-11.74% |
579.44% |
85.22% |
|---|
| ENTA |
Enanta Pharmaceuticals, Inc. |
117.76M |
0.10% |
|
|
|
|
|
5.52 |
-3.33% |
220.08% |
50.36% |
|---|
| 1835589D |
Chinook Therapeutics Inc. |
|
N/A |
|
|
|
|
|
|
|
|
|
|---|